Chellappan, Retna Raj ; Kitamura, F. ; Ohsaka, Takeo (2002) Square wave voltammetric sensing of uric acid using the self-assembly of mercaptobenzimidazole The Analyst, 127 (9). pp. 1155-1158. ISSN 0003-2654
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Official URL: https://doi.org/10.1039/B206703J
Related URL: http://dx.doi.org/10.1039/B206703J
Abstract
The self-assembled monolayer of a heterocyclic thiol, mercaptobenzimidazole (MBI) on gold (Au) electrode is successfully utilized for the voltammetric sensing of uric acid (UA). The self-assembly of MBI separates the voltammetric signal of UA from the interfering ascorbate (AA). Selective detection of UA in the presence of a large excess of AA or the simultaneous detection of UA and AA is achieved at the MBI monolayer-modified electrode. This electrode can detect as low as 1 μM of UA in the presence of 100-fold excess of AA with excellent reproducibility. The practical utility of the electrode is demonstrated by measuring the concentration of UA in human serum.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 139997 |
| Deposited On: | 03 Sep 2025 06:44 |
| Last Modified: | 03 Sep 2025 06:44 |
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