Uppu, Divakara S. S. M. ; Akkapeddi, Padma ; Manjunath, Goutham B. ; Yarlagadda, Venkateswarlu ; Hoque, Jiaul ; Haldar, Jayanta (2013) Polymers with tunable side-chain amphiphilicity as non-hemolytic antibacterial agents Chemical Communications, 49 (82). p. 9389. ISSN 1359-7345
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Official URL: https://doi.org/10.1039/C3CC43751E
Related URL: http://dx.doi.org/10.1039/C3CC43751E
Abstract
Quaternized polymers mimicking the antimicrobial peptides were created by tuning the side-chain amphiphilicity using a first-time approach of post-functionalization. They displayed excellent efficacy against pathogenic bacteria even in human plasma and membrane disruptive mode of action. The optimized polymers and degraded products were non-hemolytic.
Item Type: | Article |
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Source: | Copyright of this article belongs to Royal Society of Chemistry. |
ID Code: | 138809 |
Deposited On: | 08 Sep 2025 04:33 |
Last Modified: | 08 Sep 2025 04:33 |
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