Hoque, Jiaul ; Konai, Mohini M. ; Samaddar, Sandip ; Gonuguntala, Spandhana ; Manjunath, Goutham B. ; Ghosh, Chandradhish ; Haldar, Jayanta (2015) Selective and broad spectrum amphiphilic small molecules to combat bacterial resistance and eradicate biofilms Chemical Communications, 51 (71). pp. 13670-13673. ISSN 1359-7345
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Official URL: https://doi.org/10.1039/C5CC05159B
Related URL: http://dx.doi.org/10.1039/C5CC05159B
Abstract
Rationally designed amphiphilic small molecules selectively kill drug-sensitive and drug-resistant bacteria over mammalian cells. The small molecules disperse preformed biofilms and reduce viable bacterial count in the biofilms. Moreover, this class of membrane-active molecules disarms the development of bacterial resistance.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 138795 |
| Deposited On: | 05 Sep 2025 12:28 |
| Last Modified: | 05 Sep 2025 12:28 |
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