Uppu, D. S. S. M. ; Bhowmik, M. ; Samaddar, S. ; Haldar, Jayanta (2016) Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers Chemical Communications, 52 (25). pp. 4644-4647. ISSN 1359-7345
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Official URL: https://doi.org/10.1039/C5CC09930G
Related URL: http://dx.doi.org/10.1039/C5CC09930G
Abstract
Membrane-active agents represent a promising alternative to overcome antibiotic resistance. Here, we report cationic-amphiphilic polymers with variations in the side chain architecture such as cyclization, isomerization and unsaturation that resulted in potent antibacterial activity and low mammalian cell toxicity with a membrane-active mode of action.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 138777 |
| Deposited On: | 05 Sep 2025 11:26 |
| Last Modified: | 05 Sep 2025 11:26 |
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