Radiological qualitative assessment of ivim parameters for total variation penalty function approach: a pilot study in osteosarcoma

Abstract

Radiological based qualitative assessment of evaluated IVIM parametric maps using state-of-the-art IVIM analysis methods Bi-exponential (BE) model with adaptive Total Variation Penalty function (BE+TV) and BE with adaptive Huber Penalty function (BE+HPF) has been performed in comparison to the commonly used IVIM analysis methodologies like BE model, and segmented BE methods. BE+TV/BE+HPF preserve spatial homogeneity in the parametric images by updating them iteratively during data fitting. Experimental results showed all IVIM analysis methods showed BE+TV and BE+HPF produced comparative better noise suppression and diagnostic quality and interpretability for D* and f than other methods.