Kumar, Dhiraj ; Pandey, Poonam R ; Kundu, Gopal C (2017) Notch1-mapk signaling axis is essential in cd133+ melanoma initiating cells Journal of Cell Signaling, 02 (04). ISSN 2576-1471
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Official URL: https://doi.org/10.4172/2576-1471.1000175
Related URL: http://dx.doi.org/10.4172/2576-1471.1000175
Abstract
Our results identify the molecular mechanism of CSCs that help inthe metastasis, angiogenesis and tumor progression. Targeting Notch1-MAPK signaling axis attenuates CD133+ cells-mediated melanomaprogression. us, our study has addressed an important gap withCSCs markers and their associated function in melanoma model. Infuture, we need to nd potential therapeutic targets and agents for theprevention or treatment of CSCs mediated melanoma progression.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Journal of Cell Signaling. |
| ID Code: | 138489 |
| Deposited On: | 26 Aug 2025 06:40 |
| Last Modified: | 26 Aug 2025 06:40 |
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