Radharani, N. N. V. ; Yadav, Amit S. ; Nimma, Ramakrishna ; Kumar, T. V. Santosh ; Bulbule, Anuradha ; Chanukuppa, Venkatesh ; Kumar, Dhiraj ; Patnaik, Srinivas ; Rapole, Srikanth ; Kundu, Gopal C. (2022) Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway Cancer Cell International, 22 (1). ISSN 1475-2867
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Official URL: https://doi.org/10.1186/s12935-022-02527-9
Related URL: http://dx.doi.org/10.1186/s12935-022-02527-9
Abstract
Cancer stem cells (CSCs) play crucial role in tumor progression, drug resistance and relapse in various cancers. CSC niche is comprised of various stromal cell types including Tumor-associated macrophages (TAMs). Extrinsic ques derived from these cells help in maintenance of CSC phenotype. TAMs have versatile roles in tumor progression however their function in enrichment of CSC is poorly explored.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to BioMed Central. |
| ID Code: | 138439 |
| Deposited On: | 22 Aug 2025 12:29 |
| Last Modified: | 22 Aug 2025 12:29 |
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