Elevated mitochondrial DNA copy numbers in pediatric acute lymphoblastic leukemia: A potential biomarker for predicting inferior survival

Jain, Ayushi ; Bakhshi, Sameer ; Thakkar, Himani ; Gerards, Mike ; Singh, Archna (2017) Elevated mitochondrial DNA copy numbers in pediatric acute lymphoblastic leukemia: A potential biomarker for predicting inferior survival Pediatric Blood & Cancer, 65 (3). ISSN 1545-5009

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Official URL: https://doi.org/10.1002/pbc.26874

Related URL: http://dx.doi.org/10.1002/pbc.26874

Abstract

Studies on mitochondrial DNA copy number reveal an increase or decrease in copy number that appears to be cancer specific, but data on acute lymphoblastic leukemia have been inconsistent regarding the significance of changes in mitochondrial DNA copies. The purpose of this pilot study was to analyze mitochondrial DNA copy number and mitochondrial DNA integrity.

Item Type:Article
Source:Copyright of this article belongs to Pediatric blood & cancer.
ID Code:137927
Deposited On:18 Aug 2025 12:54
Last Modified:18 Aug 2025 12:54

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