Makwana, Kamlesh Madhusudan ; Raghothama, Srinivasarao ; Mahalakshmi, Radhakrishnan (2013) Stabilizing effect of electrostatic vs. aromatic interactions in diproline nucleated peptide β-hairpins Physical Chemistry Chemical Physics, 15 (37). p. 15321. ISSN 1463-9076
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Official URL: http://doi.org/10.1039/C3CP52770K
Related URL: http://dx.doi.org/10.1039/C3CP52770K
Abstract
The contribution of Tyr–His vs. Cys–His interacting pairs to the scaffold stability of DPro–LPro nucleated peptide β-hairpins has been examined. We present direct evidence for the superiority of the Cys–His pairs, mediated by sulphur–imidazole interactions, as added stabilizing agents of the β-hairpin scaffold.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 136843 |
| Deposited On: | 20 Aug 2025 11:29 |
| Last Modified: | 20 Aug 2025 11:29 |
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