Dendrimeric amide- and carbamate-linked lysine-based efficient molecular transporters

Yadav, Amit Kumar ; Dey, Namit ; Chattopadhyay, Sabyasachi ; Ganguli, Munia ; Fernandes, Moneesha (2017) Dendrimeric amide- and carbamate-linked lysine-based efficient molecular transporters Organic & Biomolecular Chemistry, 15 (45). pp. 9579-9584. ISSN 1477-0520

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Official URL: http://doi.org/10.1039/C7OB02552A

Related URL: http://dx.doi.org/10.1039/C7OB02552A

Abstract

Amide- and carbamate-linked dendrimeric oligomers are reported as molecular transporters. They effectively complex with pDNA and transport it into cells at an efficiency superior to Lipofectamine, when complexation is carried out by incubation overnight. The carbamate-linked K2C is superior to amide-linked K2A; their pDNA complexes have very low associated cytotoxicity.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:136628
Deposited On:24 Jun 2025 12:36
Last Modified:24 Jun 2025 12:36

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