First stereoselective total synthesis of cryptomoscatone E1 and synthesis of (+)-goniothalamin via an asymmetric acetate aldol reaction

Yadav, Jhillu Singh ; Bhunia, Dinesh Chandra ; Ganganna, Bogonda ; Singh, Vinay Kumar (2013) First stereoselective total synthesis of cryptomoscatone E1 and synthesis of (+)-goniothalamin via an asymmetric acetate aldol reaction RSC Advances, 3 (15). p. 5254. ISSN 2046-2069

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Official URL: http://doi.org/10.1039/C3Ra23167D

Related URL: http://dx.doi.org/10.1039/C3Ra23167D

Abstract

A stereoselective total synthesis of (+)-goniothalamin and cryptomoscatone E1 have been described. The synthetic strategy involves an asymmetric acetate aldol reaction, Evans acetal intramolecular oxa-Michael reaction, ring-closing metathesis, Horner–Wadsworth–Emmons reaction and lactonization as the key steps.

Item Type:Article
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ID Code:135743
Deposited On:11 Aug 2023 09:28
Last Modified:11 Aug 2023 09:28

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