Sharada, Ambati ; Rao, Kundeti ; Yadav, Jhillu ; Rao, Tadikamalla ; Nagaiah, Kommu (2017) First Stereoselective Synthesis of (6R,7R,8S)-8-Chlorogoniodiol Synthesis, 49 (11). pp. 2483-2487. ISSN 0039-7881
Full text not available from this repository.
Official URL: http://doi.org/10.1055/S-0036-1588972
Related URL: http://dx.doi.org/10.1055/S-0036-1588972
Abstract
A stereoselective synthesis of (6R,7R,8S)-8-chlorogoniodiol has been achieved in a linear sequence of 12 steps and 19.8% overall yield from cinnamyl alcohol. The key steps include Sharpless asymmetric epoxidation, regioselective ring opening of epoxide, indium-mediated Barbier allylation, and Still–Gennari olefination.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Georg Thieme Verlag KG. |
| ID Code: | 135691 |
| Deposited On: | 10 Aug 2023 08:10 |
| Last Modified: | 10 Aug 2023 08:10 |
Repository Staff Only: item control page
