Total synthesis of cytotoxic pyranone B

Maheshwar Gonela, Uma ; Kanikarapu, Suresh ; Yadav, Jhillu S. (2018) Total synthesis of cytotoxic pyranone B Synthetic Communications, 48 (24). pp. 3133-3138. ISSN 0039-7911

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Official URL: http://doi.org/10.1080/00397911.2018.1536787

Related URL: http://dx.doi.org/10.1080/00397911.2018.1536787

Abstract

The first stereoselective total synthesis of cytotoxic diacetylene pyranone B is described. The key steps involved in the synthesis are base-induced elimination protocol to generate the chiral acetylenic alcohol and selective cross-coupling of unsymmetrical terminal acetylenes.

Item Type:Article
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ID Code:135675
Deposited On:27 Jul 2023 10:50
Last Modified:27 Jul 2023 10:50

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