Ashokkumar, Pichandi ; Ashoka, Anila Hoskere ; Collot, Mayeul ; Das, Amitava ; Klymchenko, Andrey S. (2019) A fluorogenic BODIPY molecular rotor as an apoptosis marker Chemical Communications, 55 (48). pp. 6902-6905. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/C9CC03242H
Related URL: http://dx.doi.org/10.1039/C9CC03242H
Abstract
Based on a BODIPY molecular rotor and a zinc–dipicolylamine receptor, we designed a fluorogenic probe for the detection of apoptosis. Being poorly emissive in solution and with healthy cells, it selectively binds phosphatidylserine of early apoptotic cells and internalizes into late apoptotic cells, lighting up its green fluorescence.
Item Type: | Article |
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Source: | Copyright of this article belongs to Royal Society of Chemistry. |
ID Code: | 135427 |
Deposited On: | 24 Jan 2023 04:59 |
Last Modified: | 24 Jan 2023 04:59 |
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