Interactive luminescent gold nanocluster embedded dsDNA and cisplatin as model nanoparticles for cancer theranostics

Chatterjee, Bandhan ; Sahoo, Amaresh Kumar ; Ghosh, Siddhartha Sankar ; Chattopadhyay, Arun (2016) Interactive luminescent gold nanocluster embedded dsDNA and cisplatin as model nanoparticles for cancer theranostics RSC Advances, 6 (114). pp. 113053-113057. ISSN 2046-2069

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Official URL: http://doi.org/10.1039/C6RA24325H

Related URL: http://dx.doi.org/10.1039/C6RA24325H

Abstract

Plasmid DNA embedded with luminescent gold nanoclusters were reacted with cisplatin to form composite nanoparticles (composite NPs) for theranostic applications. The composite NPs delivered the cisplatin to cervical cancer HeLa cells in vitro, inducing apoptosis mediated cell death. The luminescent gold nanoclusters were simultaneously used for cellular imaging.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry
ID Code:135424
Deposited On:24 Jan 2023 04:51
Last Modified:24 Jan 2023 04:51

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