Shigdar, Sarah ; Li, Yong ; Bhattacharya, Santanu ; O’Connor, Michael ; Pu, Chunwen ; Lin, Jia ; Wang, Tao ; Xiang, Dongxi ; Kong, Lingxue ; Wei, Ming Q. ; Zhu, Yimin ; Zhou, Shufeng ; Duan, Wei (2014) Inflammation and cancer stem cells Cancer Letters, 345 (2). pp. 271-278. ISSN 0304-3835
Full text not available from this repository.
Official URL: http://doi.org/10.1016/j.canlet.2013.07.031
Related URL: http://dx.doi.org/10.1016/j.canlet.2013.07.031
Abstract
Cancer stem cells are becoming recognised as being responsible for metastasis and treatment resistance. The complex cellular and molecular network that regulates cancer stem cells and the role that inflammation plays in cancer progression are slowly being elucidated. Cytokines, secreted by tumour associated immune cells, activate the necessary pathways required by cancer stem cells to facilitate cancer stem cells progressing through the epithelial-mesenchymal transition and migrating to distant sites. Once in situ, these cancer stem cells can secrete their own attractants, thus providing an environment whereby these cells can continue to propagate the tumour in a secondary niche.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 134122 |
| Deposited On: | 05 Jan 2023 06:43 |
| Last Modified: | 05 Jan 2023 06:43 |
Repository Staff Only: item control page
