Kotha, Surya Srinivas ; Sekar, Govindasamy (2015) Metal free synthesis of α-keto amides from 2-hydroxy acetophenones through domino alcohol oxidation–oxidative amidation reaction Tetrahedron Letters, 56 (46). pp. 6323-6326. ISSN 0040-4039
Full text not available from this repository.
Official URL: http://doi.org/10.1016/j.tetlet.2015.09.053
Related URL: http://dx.doi.org/10.1016/j.tetlet.2015.09.053
Abstract
An efficient method for the synthesis of α-keto amides using 2-iodoxybenzoic acid (IBX) promoted domino alcohol oxidation and oxidative amidation reaction sequence between 2-oxoalcohols and amines under metal-free conditions is developed. In this protocol, IBX is used as an oxidizing agent to synthesize the α-keto amides, which makes this methodology highly efficient, practical, and environmentally benign.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 132144 |
| Deposited On: | 14 Dec 2022 06:32 |
| Last Modified: | 14 Dec 2022 06:32 |
Repository Staff Only: item control page
