Majumder, Poulami ; Bhunia, Sukanya ; Chaudhuri, Arabinda (2018) A lipid-based cell penetrating nano-assembly for RNAi-mediated anti-angiogenic cancer therapy Chemical Communications, 54 (12). pp. 1489-1492. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/C7CC08517F
Related URL: http://dx.doi.org/10.1039/C7CC08517F
Abstract
Limited tumor tissue penetration is one of the key impeding factors retarding successful in vivo exploitations of anti-angiogenic cancer therapy. Herein we report on the design of a cell penetrating peptide-decorated lipid nano-assembly which, upon systemic administration, induces significant mouse tumor growth inhibition via enhanced tumor infiltration of encapsulated anti-angiogenic siRNA.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry |
| ID Code: | 132090 |
| Deposited On: | 14 Dec 2022 04:02 |
| Last Modified: | 14 Dec 2022 04:02 |
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