Senthilkumar, Soundararasu ; Prasad, Sure Siva ; Das, Amrita ; Baskaran, Sundarababu (2015) One‐Pot Synthesis of Hydrophobically Modified Iminosugar C ‐Alkynylglycosides: Facile Synthesis of Polyhydroxy Tetrahydroindolizines Chemistry - A European Journal, 21 (45). pp. 15914-15918. ISSN 0947-6539
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Official URL: http://doi.org/10.1002/chem.201503047
Related URL: http://dx.doi.org/10.1002/chem.201503047
Abstract
A mild and efficient one-pot method has been developed for the stereoselective synthesis of structurally diverse novel iminosugar C-alkynylglycosides (see scheme). The generality of this methodology has been demonstrated with a wide variety of amines and copper acetylides. This one-pot method has been exploited in the synthesis of a new class of DNA cross-linking agents, polyhydroxy 1-vinyl-tetrahydroindolizine derivatives.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| ID Code: | 131840 |
| Deposited On: | 09 Dec 2022 04:51 |
| Last Modified: | 09 Dec 2022 04:51 |
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