Neighbouring group assisted sulfonamide cleavage of Sharpless aminols under acetonation conditions

Chandrasekhar, S. ; Mohapatra, Suchismita (1998) Neighbouring group assisted sulfonamide cleavage of Sharpless aminols under acetonation conditions Tetrahedron Letters, 39 (7). pp. 695-698. ISSN 00404039

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Official URL: http://doi.org/10.1016/S0040-4039(97)10638-4

Related URL: http://dx.doi.org/10.1016/S0040-4039(97)10638-4

Abstract

It is accidentally observed that N-Ts cleavage and simultaneous protection of resulting free amino group as acetonide with the adjacent hydroxy group is achieved in one pot. Neighbouring carboxylic ester group is essential for this transformatio

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