Acylation of alcohols with acetic anhydride catalyzed by TaCl5: Some implications in kinetic resolution

Chandrasekhar, S. ; Ramachander, T. ; Takhi, Mohamed (1998) Acylation of alcohols with acetic anhydride catalyzed by TaCl5: Some implications in kinetic resolution Tetrahedron Letters, 39 (20). pp. 3263-3266. ISSN 00404039

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Official URL: http://doi.org/10.1016/S0040-4039(98)00465-1

Related URL: http://dx.doi.org/:10.1016/S0040-4039(98)00465-1

Abstract

TaCl5 and TaCl5-Silica gel have been effectively used as Lewis acid catalysts for acetylation of alcohols. Also TaCl5-Chiral ligands have been used for kinetic resolution of 2° alcohols albeit in low ees. TaCl5 and TaCl5-Silica gel have been effectively used as Lewis acid catalysts for acetylation of alcohols. Also TaCl5-Chiral ligands have been used for kinetic resolution of 2° alcohols.

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