Chandrasekhar, S. ; Mohapatra, Suchismita ; Yadav, J.S. (1999) Practical synthesis of Abbott amino-diol: A core unit of the potent renin inhibitor Zankiren Tetrahedron, 55 (15). pp. 4763-4768. ISSN 00404020
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Official URL: http://doi.org/10.1016/S0040-4020(99)00148-9
Related URL: http://dx.doi.org/10.1016/S0040-4020(99)00148-9
Abstract
Abbott amino-diol (2S,3R,4S)-2-amino-1-cyclohexyl-6-methyl heptane-3,4-diol 1, a main structural constituent of the orally active renin inhibitor Zankiren has been synthesized using Sharpless asymmetric aminohydroxylation as the key step. Enantioselective synthesis of Abbott Amino-diol is achieved using Sharpless aminohydroxylation as the key step.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd. |
| ID Code: | 131441 |
| Deposited On: | 06 Dec 2022 13:27 |
| Last Modified: | 06 Dec 2022 13:27 |
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