Unexpected Formation of 3-Substituted 1,2,3,4-Tetrahydroisoquinolines during Tosylation of N,N-dibenzylaminols

Chandrasekhar, S. ; Mohanty, Pradyumna K. ; Harikishan, K. ; Sasmal, Pradip K. (1999) Unexpected Formation of 3-Substituted 1,2,3,4-Tetrahydroisoquinolines during Tosylation of N,N-dibenzylaminols Organic Letters, 1 (6). pp. 877-878. ISSN 1523-7060

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Official URL: http://doi.org/10.1021/ol9901220

Related URL: http://dx.doi.org/10.1021/ol9901220

Abstract

An efficient new entry toward the construction of 3-substituted 1,2,3,4-tetrahydroisoquinolines from N,N-dibenzyl-α-aminols is reported via intramolecular Friedel−Crafts cyclization of in situ generated tosylate intermediate.

Item Type:Article
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ID Code:131436
Deposited On:06 Dec 2022 13:21
Last Modified:06 Dec 2022 13:21

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