Reddy, Ch. Raji ; Madhavi, P. Phani ; Chandrasekhar, S. (2010) Synthesis of a diarylheptanoid, (+)-centrolobine Tetrahedron: Asymmetry, 21 (1). pp. 103-105. ISSN 09574166
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Official URL: http://doi.org/10.1016/j.tetasy.2010.01.002
Related URL: http://dx.doi.org/10.1016/j.tetasy.2010.01.002
Abstract
A chiron approach for the total synthesis of (+)-centrolobine has been described from the commercially available aldehyde 3 employing an acid-catalyzed stereoselective formation of tetrahydropyran ring as the key step. The desired molecule was accomplished in eight steps with 62% overall yield.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd |
| ID Code: | 131420 |
| Deposited On: | 06 Dec 2022 12:51 |
| Last Modified: | 06 Dec 2022 12:51 |
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