Hydroxyphthalimide allied triazole-pyrrolidine catalyst for asymmetric Michael additions in water

Chandrasekhar, Srivari ; Kumar, Togapur Pavan ; Haribabu, Kothapalli ; Reddy, Chada Raji (2010) Hydroxyphthalimide allied triazole-pyrrolidine catalyst for asymmetric Michael additions in water Tetrahedron: Asymmetry, 21 (19). pp. 2372-2375. ISSN 09574166

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Official URL: http://doi.org/10.1016/j.tetasy.2010.08.012

Related URL: http://dx.doi.org/10.1016/j.tetasy.2010.08.012

Abstract

A new hydroxyphthalimide-coupled triazole-pyrrolidine derivative has been synthesized and demonstrated as an efficient and stereoselective organocatalyst for the asymmetric Michael addition reaction of ketones to nitro olefins at room temperature. Good yields and high selectivities were achieved when benzoic acid was used in combination with organocatalyst 1, employing water as the reaction medium.

Item Type:Article
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ID Code:131389
Deposited On:06 Dec 2022 12:03
Last Modified:06 Dec 2022 12:03

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