aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle

Chandrasekhar, Srivari ; Pushpavalli, Sreerangam N.C.V.L. ; Chatla, Srinivas ; Mukhopadhyay, Debasmita ; Ganganna, Bogonda ; Vijeender, Kandi ; Srihari, Pabbaraja ; Reddy, Chada Raji ; Janaki Ramaiah, M. ; Bhadra, Utpal (2012) aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle Bioorganic & Medicinal Chemistry Letters, 22 (1). pp. 645-648. ISSN 0960894X

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Official URL: http://doi.org/10.1016/j.bmcl.2011.10.061

Related URL: http://dx.doi.org/10.1016/j.bmcl.2011.10.061

Abstract

aza-Flavanones have been identified as a new class of selective microRNA inhibitors. These compounds were found to arrest cell cycle via a novel cross species microRNA-dependent regulatory pathway interpreting an unexpected link between cell cycle arrest and microRNA mediated control in cancer.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:aza-Flavones;Micro;RNA inhibitors;Drosophila;Cell cycle arrest;Apoptosis
ID Code:131367
Deposited On:06 Dec 2022 11:27
Last Modified:06 Dec 2022 11:27

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