Formal synthesis of fumonisin B1, a potent sphingolipid biosynthesis inhibitor

Chandrasekhar, Srivari ; Sreelakshmi, Lella (2012) Formal synthesis of fumonisin B1, a potent sphingolipid biosynthesis inhibitor Tetrahedron Letters, 53 (26). pp. 3233-3236. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2012.04.030

Related URL: http://dx.doi.org/10.1016/j.tetlet.2012.04.030

Abstract

The formal total synthesis of the important toxin fumonisin B1 is achieved from simple raw materials in a convergent manner. The key functionalities are derived from MacMillan α-hydroxylation, sharpless asymmetric dihydroxylation and ring-closing metathesis.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:d-Mannitol;Fumonisin B1;Mac;Millan α-hydroxylation;Sphingolipid;Ring-closing metathesis
ID Code:131358
Deposited On:06 Dec 2022 11:06
Last Modified:06 Dec 2022 11:06

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