Murthy, Akondi Srirama ; Mahipal, Bodugum ; Chandrasekhar, Srivari (2012) Asymmetric Synthesis of the C14-C26 Building Block of Eribulin Mesylate European Journal of Organic Chemistry, 2012 (35). pp. 6959-6966. ISSN 1434193X
Full text not available from this repository.
Official URL: http://doi.org/10.1002/ejoc.201201119
Related URL: http://dx.doi.org/10.1002/ejoc.201201119
Abstract
An alternative route for the synthesis of the C14–C26 building block of the anticancer drug eribulin mesylate is described. The key steps involved in the synthesis are a Julia–Kocienski olefination between aldehyde 4 and sulfone 5 and a tandem Sharpless asymmetric dihydroxylation/SN2 cyclisation reaction on mesyl compound 3.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley & Sons, Inc |
| ID Code: | 131348 |
| Deposited On: | 06 Dec 2022 10:54 |
| Last Modified: | 06 Dec 2022 10:54 |
Repository Staff Only: item control page
