Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles Amicable for Automation

Kavitha, Mitta ; Mahipal, Bodugam ; Mainkar, Prathama ; Chandrasekhar, Srivari (2013) Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles Amicable for Automation Combinatorial Chemistry & High Throughput Screening, 16 (8). pp. 657-663. ISSN 13862073

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Official URL: http://doi.org/10.2174/1386207311316080009

Related URL: http://dx.doi.org/10.2174/1386207311316080009

Abstract

A three-component 3+2 cycloaddition reaction followed by Suzuki coupling reaction was carried out to synthesize a library of compounds using automation (parallel synthesizer). Scaffolds that are unexplored in literature were used for the synthesis of library. The iodo-triazoles formed by 3+2 cycloaddition reaction were coupled with boronic acids to get tri-substituted triazoles.

Item Type:Article
Source:Copyright of this article belongs to Bentham Science Publishers
ID Code:131342
Deposited On:06 Dec 2022 10:46
Last Modified:06 Dec 2022 10:46

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