Naresh, Tumma ; Kumar, Togapur Pavan ; Haribabu, Kothapalli ; Chandrasekhar, Srivari (2014) AZT-prolinamide: the nucleoside derived pyrrolidine catalysts for asymmetric aldol reactions using water as solvent Tetrahedron: Asymmetry, 25 (18-19). pp. 1340-1345. ISSN 09574166
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Official URL: http://doi.org/10.1016/j.tetasy.2014.08.007
Related URL: http://dx.doi.org/10.1016/j.tetasy.2014.08.007
Abstract
New pyrrolidine catalysts based on a nucleoside and proline, AZT-prolinamides, were synthesized and successfully employed for the enantioselective direct aldol reaction of aldehydes with ketones. These catalysts proved to be effective in promoting the reaction, in additive free water media with 15 mol % loading. The products, β-hydroxy carbonyl compounds were obtained in high yields and stereoselectivities.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Ltd |
ID Code: | 131328 |
Deposited On: | 06 Dec 2022 10:20 |
Last Modified: | 06 Dec 2022 10:20 |
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