Scalable synthesis of the unusual amino acid segment (ADMOA unit) of marine anti-inflammatory peptide: solomonamide A

Kavitha, Nerella ; Chandrasekhar, Srivari (2015) Scalable synthesis of the unusual amino acid segment (ADMOA unit) of marine anti-inflammatory peptide: solomonamide A Organic & Biomolecular Chemistry, 13 (22). pp. 6242-6248. ISSN 1477-0520

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Official URL: http://doi.org/10.1039/C5OB00481K

Related URL: http://dx.doi.org/10.1039/C5OB00481K

Abstract

The most abundantly available hexose sugar, D-glucose has been converted to protected 4-amino(2′amino-4′-hydroxy phenyl)-3,5-dihydroxy-2-methyl-6-oxo hexanoic acid (protected ADMOA, 3), the unusual amino acid present in marine natural product solomonamide A in gram quantities involving easy to operate chemical transformations.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry
ID Code:131319
Deposited On:06 Dec 2022 10:07
Last Modified:06 Dec 2022 10:07

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