Expanding the tetrahydroquinoline pharmacophore

Goli, Navya ; Mainkar, Prathama S. ; Kotapalli, Sudha Sravanti ; K, Tejaswini ; Ummanni, Ramesh ; Chandrasekhar, Srivari (2017) Expanding the tetrahydroquinoline pharmacophore Bioorganic & Medicinal Chemistry Letters, 27 (8). pp. 1714-1720. ISSN 0960894X

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Official URL: http://doi.org/10.1016/j.bmcl.2017.02.077

Related URL: http://dx.doi.org/10.1016/j.bmcl.2017.02.077

Abstract

Tetrahydroquinoline is a privileged scaffold with a large number of biological applications. The tetrahydroquinoline pharmacophore has been expanded to yield 34 compounds. Biological screening of these compounds led to the identification of tetrahydroquinoline as neurotropic agents not reported earlier.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:Povarov reaction;Tetrahydroquinoline;Neurotropic agents
ID Code:131304
Deposited On:06 Dec 2022 09:43
Last Modified:06 Dec 2022 09:43

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