Kranthikumar, Ramagonolla ; Mainkar, Prathama S. ; Sukumar, Genji ; Chegondi, Rambabu ; Chandrasekhar, Srivari (2019) Tetrahydrothiopyran-4-one as Five-Carbon Source for Scalable Synthesis of (±)-Tapentadol Organic Process Research & Development, 23 (7). pp. 1369-1373. ISSN 1083-6160
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Official URL: http://doi.org/10.1021/acs.oprd.9b00121
Related URL: http://dx.doi.org/10.1021/acs.oprd.9b00121
Abstract
The improved process for the synthesis of (±)-tapentadol, the FDA-approved analgesic drug, is achieved from tetrahydrothiopyran-4-one as the five-carbon source.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society |
| ID Code: | 131288 |
| Deposited On: | 06 Dec 2022 09:04 |
| Last Modified: | 06 Dec 2022 09:04 |
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