Donikela, Sangeetha ; Nayani, Kiranmai ; Nomula, Vishnuvardhan ; Mainkar, Prathama S. ; Chandrasekhar, Srivari (2019) Gram-Scale Solution-Phase Synthesis of Heptapeptide Side Chain of Teixobactin Synlett, 30 (20). pp. 2268-2272. ISSN 0936-5214
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Official URL: http://doi.org/10.1055/s-0039-1690232
Related URL: http://dx.doi.org/10.1055/s-0039-1690232
Abstract
We report herein a scalable synthesis of linear heptapeptide side chain of the depsipeptide natural product teixobactin through solution phase. The synthesis of heptapeptide was achieved through an efficient coupling of suitably protected tripeptide and tetrapeptide comprising of three d-amino acids and four usual l-amino acid subunits.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Georg Thieme Verlag KG |
| ID Code: | 131281 |
| Deposited On: | 06 Dec 2022 08:58 |
| Last Modified: | 06 Dec 2022 08:58 |
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