Diastereoselective Formal Synthesis of Polycyclic Meroterpenoid (±)-Cochlearol A

Venkatesh, Telugu ; Mainkar, Prathama S. ; Chandrasekhar, Srivari (2021) Diastereoselective Formal Synthesis of Polycyclic Meroterpenoid (±)-Cochlearol A The Journal of Organic Chemistry, 86 (7). pp. 5412-5416. ISSN 0022-3263

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Official URL: http://doi.org/10.1021/acs.joc.1c00205

Related URL: http://dx.doi.org/10.1021/acs.joc.1c00205

Abstract

A formal synthesis of (±)-cochlearol A was accomplished. The synthesis features Suzuki coupling and Friedel–Crafts cyclization as a convergent strategy to the functionalized tetralone ring and an intramolecular construction of the C/D ring involving sequential epoxide formation/acetal formation.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:131269
Deposited On:06 Dec 2022 08:39
Last Modified:06 Dec 2022 08:39

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