Total synthesis of remdesivir

Kumar Palli, Kishore ; Ghosh, Palash ; Krishna Avula, Shiva ; Sridhara Shanmukha Rao, B. ; Patil, Amol D. ; Ghosh, Subhash ; Sudhakar, Gangarajula ; Raji Reddy, Chada ; Mainkar, Prathama S. ; Chandrasekhar, Srivari (2022) Total synthesis of remdesivir Tetrahedron Letters, 88 . p. 153590. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2021.153590

Related URL: http://dx.doi.org/10.1016/j.tetlet.2021.153590

Abstract

Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:Remdesivir;Nucleotide;Nucleoside;COVID-19;RdRp
ID Code:131267
Deposited On:06 Dec 2022 08:37
Last Modified:06 Dec 2022 08:37

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