Cascade aryne insertion/vinylogous aldol reaction of vinyl-substituted β-keto/enol carbonyls

Chaitanya, Nandikolla Krishna ; Rao, Y. N. Sambasiva ; Choutipalli, Venkata Surya Kumar ; Mainkar, Prathama S. ; Subramanian, Venkatesan ; Chandrasekhar, Srivari (2022) Cascade aryne insertion/vinylogous aldol reaction of vinyl-substituted β-keto/enol carbonyls Chemical Communications, 58 (19). pp. 3178-3181. ISSN 1359-7345

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Official URL: http://doi.org/10.1039/D1CC06810E

Related URL: http://dx.doi.org/10.1039/D1CC06810E

Abstract

Cyclic and acyclic vinyl substituted β-keto/enol carbonyl substrates, on reaction with arynes, result in differentially substituted naphthyl carbocycles, hitherto difficult to synthesize with existing protocols. While the substitutions on the arynes have no role, the ring size of the cyclic β-keto/enol esters has a profound influence on the product formation.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry
ID Code:131266
Deposited On:06 Dec 2022 08:35
Last Modified:06 Dec 2022 08:35

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