ChemInform Abstract: Stereocontrolled Construction of Key Building Blocks for the Total Synthesis of Amphoteronolide B and Amphotericin B.

NICOLAOU, K. C. ; DAINES, R. A. ; UENISHI, J. ; LI, W. S. ; PAPAHATJIS, D. P. ; CHAKRABORTY, T. K. (2016) ChemInform Abstract: Stereocontrolled Construction of Key Building Blocks for the Total Synthesis of Amphoteronolide B and Amphotericin B. ChemInform, 18 (33). ISSN 09317597

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Official URL: http://doi.org/10.1002/chin.198733354

Related URL: http://dx.doi.org/10.1002/chin.198733354

Abstract

In order to achieve a total synthesis of amphotericin B, a clinically used antifungal agent from Streptomyces nodosus, and its aglycon amphoteronolide B, the required building blocks (IV), (VIII), (XIV) and (XVII) are prepared as shown in the scheme.

Item Type:Article
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ID Code:131221
Deposited On:06 Dec 2022 04:22
Last Modified:06 Dec 2022 04:22

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