Chemoselective reduction of α-keto amides using nickel catalysts

Mamillapalli, N. Chary ; Sekar, Govidasamy (2014) Chemoselective reduction of α-keto amides using nickel catalysts Chemical Communications, 50 (58). pp. 7881-7884. ISSN 1359-7345

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Official URL: http://doi.org/10.1039/c4cc02744b

Related URL: http://dx.doi.org/10.1039/c4cc02744b

Abstract

Ni-catalysts are used for the first time to synthesize highly important α-hydroxy amides and β-amino alcohols from α-keto amides by chemoselective and complete reduction using hydrosilanes. Chemoselective complete reduction of α-keto amides in the presence of a simple amide group is a key benefit of these Ni-catalysts.

Item Type:Article
ID Code:130704
Deposited On:29 Nov 2022 08:39
Last Modified:29 Nov 2022 08:39

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