Baylis-Hillman Reaction: In Situ Generated Isoquinolinium Species as Excellent Electrophiles for Coupling with Alkyl Acrylates and Acrylonitrile

Basavaiah, Deevi ; Thamizharasi, Perumal (2017) Baylis-Hillman Reaction: In Situ Generated Isoquinolinium Species as Excellent Electrophiles for Coupling with Alkyl Acrylates and Acrylonitrile European Journal of Organic Chemistry, 2017 (34). pp. 5135-5140. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201700743

Related URL: http://dx.doi.org/10.1002/ejoc.201700743

Abstract

Isoquinolinium species, generated in situ from 2-alkynylbenzaldehydes, arylamines, and silver trifluoromethanesulfonate (AgOTf), are utilized as excellent electrophiles for Baylis–Hillman coupling with alkyl acrylates and acrylonitrile in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) to provide 1,2,3-trisubstituted dihydroisoquinoline derivatives.

Item Type:Article
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ID Code:130145
Deposited On:02 Dec 2022 05:56
Last Modified:05 Dec 2022 05:56

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