Less reactive ketones as electrophiles and acrylamides as activated alkenes in intramolecular Baylis–Hillman reaction: facile synthesis of functionalized γ-lactam frameworks

Basavaiah, Deevi ; Reddy, Guddeti Chandrashekar ; Bharadwaj, Kishor Chandra (2014) Less reactive ketones as electrophiles and acrylamides as activated alkenes in intramolecular Baylis–Hillman reaction: facile synthesis of functionalized γ-lactam frameworks Tetrahedron, 70 (43). pp. 7991-7995. ISSN 0040-4020

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Official URL: http://doi.org/10.1016/j.tet.2014.08.045

Related URL: http://dx.doi.org/10.1016/j.tet.2014.08.045

Abstract

Less reactive ketones and acrylamides have been successfully employed as electrophiles and activated alkenes, respectively, in intramolecular Baylis–Hillman reaction, thus providing a facile protocol for obtaining functionalized α-methylene-γ-lactam derivatives.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:130130
Deposited On:02 Dec 2022 05:57
Last Modified:02 Dec 2022 05:57

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