A Novel Antigen, Otubain Cysteine Peptidase of Leishmania donovani, for the Serodiagnosis of Visceral Leishmaniasis and for Monitoring Treatment Response

Kamran, Mohd ; Ejazi, Sarfaraz Ahmad ; Choudhury, Somsubhra Thakur ; Bhattacharyya, Anirban ; Tanishka, Km ; Pandey, Krishna ; Das, Vidya Nand Ravi ; Das, Pradeep ; da Silva, Fernando Oliveira ; Costa, Dorcas Lamounier ; Costa, Carlos Henrique Nery ; Rahaman, Mehebubar ; Goswami, Rama Prosad ; Ali, Nahid (2021) A Novel Antigen, Otubain Cysteine Peptidase of Leishmania donovani, for the Serodiagnosis of Visceral Leishmaniasis and for Monitoring Treatment Response Clinical Infectious Diseases, 73 (7). pp. 1281-1283. ISSN 1058-4838

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Official URL: http://doi.org/10.1093/cid/ciab435

Related URL: http://dx.doi.org/10.1093/cid/ciab435

Abstract

Tests for visceral leishmaniasis (VL) are not uniformly effective for all endemic regions. In a serological assay, a novel antigen, otubain cysteine peptidase, compared with rK39, showed comparable sensitivity with Indian VL serum samples and prominently increased sensitivity with Brazilian samples, as well as improved monitoring of the treatment response.

Item Type:	Article
Source:	Copyright of this article belongs to Oxford University Press
Keywords:	Leishmaniasis, diagnosis, serology, rK39, lateral flow assay
ID Code:	130128
Deposited On:	29 Nov 2022 03:47
Last Modified:	29 Nov 2022 03:47

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