Nair, Lakshmi V. ; Philips, Divya S. ; Jayasree, Ramapurath S. ; Ajayaghosh, Ayyappanpillai (2013) A Near-Infrared Fluorescent Nanosensor (AuC@Urease) for the Selective Detection of Blood Urea Small, 9 (16). pp. 2673-2677. ISSN 16136810
Full text not available from this repository.
Official URL: http://doi.org/10.1002/smll.201300213
Related URL: http://dx.doi.org/10.1002/smll.201300213
Abstract
The use of a nanosensor (AuC@Urease) based on an NIR-emitting gold cluster and urease enzyme selectively detects urea in whole blood. The detection is based on an enzyme-specific conversion of urea to ammonium ions which facilitates pH-induced aggregation of AuC, leading to fluorescence quenching. This method does not interfere with urease inactive analytes or the autofluorescence of blood as confirmed by comparable urea levels obtained by AuC@Urease and standard clinical methods within an error limit of ±3%.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley & Sons, Inc. |
| ID Code: | 130094 |
| Deposited On: | 29 Nov 2022 03:40 |
| Last Modified: | 29 Nov 2022 03:40 |
Repository Staff Only: item control page
