Stepwise control of host–guest interaction using a coordination polymer gel

Mukhopadhyay, Rahul Dev ; Das, Gourab ; Ajayaghosh, Ayyappanpillai (2018) Stepwise control of host–guest interaction using a coordination polymer gel Nature Communications, 9 (1). ISSN 2041-1723

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Official URL: http://doi.org/10.1038/s41467-018-04303-8

Related URL: http://dx.doi.org/10.1038/s41467-018-04303-8

Abstract

Precise control of host–guest interaction as seen in biological processes is difficult to achieve with artificial systems. Herein we have exploited the thermodynamic benefits of a system in equilibrium to achieve controlled stepwise release and capture of cyclodextrin (guest) using a coordination polymer (Mg-CP) as the host and temperature as the stimulus. Since temperature is not a precision stimulus for artificial host–guest interaction, the present system is a distinct prototype that manifests temperature-controlled natural host–guest interaction. The described coordination polymeric host system, when incorporated into a hydrogel matrix, provides a microenvironment that facilitates the stepwise release of α-CD in response to temperature variation within a quasi-solid state. The work demonstrated here may pave the way towards thermally controlled delivery and monitoring of otherwise spectroscopically silent molecules such as cyclodextrins.

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ID Code:129967
Deposited On:28 Nov 2022 11:37
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