Hatial, Ishita ; Jana, Saibal ; Bisai, Shrabani ; Das, Manasmita ; Ghosh, Ananta Kumar ; Anoop, Anakuthil ; Basak, Amit (2014) Trienediynes on a 1,3,5-trisubstituted benzene template: a new approach for enhancement of reactivity RSC Advances, 4 (53). p. 28041. ISSN 2046-2069
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Official URL: http://doi.org/10.1039/C4Ra04794J
Related URL: http://dx.doi.org/10.1039/C4Ra04794J
Abstract
The synthesis of trienediynes based on a 1,3,5-trisubstituted benzene template is described. The presence of three adjacent enediyne moieties in the dendritic core exerted a cooperative effect to bring down the onset temperature for Bergman cyclization leading to increased DNA cleavage in a shorter time.
Item Type: | Article |
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Source: | Copyright of this article belongs to Royal Society of Chemistry. |
ID Code: | 129963 |
Deposited On: | 05 Dec 2022 05:36 |
Last Modified: | 05 Dec 2022 05:36 |
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