Structure activity studies on the phenolic substrates in microsomal hydroxylation

Singh, Harkishan ; Gombar, Vijay ; Jain, D. V. S. (1980) Structure activity studies on the phenolic substrates in microsomal hydroxylation Proceedings of the Indian Academy of Sciences - Chemical Sciences, 89 (1). pp. 77-86. ISSN 0253-4134

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Official URL: http://www.ias.ac.in/j_archive/chemsci/89/3/77-86/...

Related URL: http://dx.doi.org/10.1007/BF02842326

Abstract

Quantitative structure-activity relationships have been developed for three series of phenolic substrates viz. phenols, hydroxyindoles and tyramines in microsomal hydroxylation. The Fujita-Ban group contributions of various substituents have been calculated. Mono-, bi-and tri-substituted phenols have been investigated in the light of the linear free energy related model also.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Quantitative Structure-activity Relationships; Fujita-ban Group Contributions; Hansch Analysis; Phenolic Substrates; Microsomal Hydroxylation
ID Code:12942
Deposited On:11 Nov 2010 08:22
Last Modified:16 May 2016 22:11

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