Ligand-Assisted Heteroaryl C(sp2 )−H Bond Activation by a Cationic Ruthenium(II) Complex for Alkenylation of Heteroarenes with Alkynes Directed by Biorelevant Heterocycles

Pipaliya, Bhavin V. ; Chakraborti, Asit K. (2017) Ligand-Assisted Heteroaryl C(sp2 )−H Bond Activation by a Cationic Ruthenium(II) Complex for Alkenylation of Heteroarenes with Alkynes Directed by Biorelevant Heterocycles ChemCatChem, 9 (22). pp. 4191-4198. ISSN 18673880

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Official URL: http://doi.org/10.1002/cctc.201701016

Related URL: http://dx.doi.org/10.1002/cctc.201701016

Abstract

Alkenylation of heteroarenes with alkynes has been achieved through ligand-assisted heteroaryl C(sp2)−H bond activation by an in situ generated cationic RuII complex directed by the biorelevant heterocyclic scaffolds benzothiazole and benzoxazole, giving broad scope with respect to the heteroarenes (thiophene, furan, N-methyl pyrrole, and 3-indole) and the alkynes (diaryl, dialkyl, and aryl alkyl) in high yields and with high stereo- and regioselectivities.

Item Type:Article
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ID Code:129393
Deposited On:16 Nov 2022 06:02
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