Etiopathogenesis of acute hepatic failure: Eastern versus Western countries

ACHARYA, SK ; BATRA, Y ; HAZARI, S ; CHOUDHURY, V ; PANDA, SK ; DATTAGUPTA, S (2002) Etiopathogenesis of acute hepatic failure: Eastern versus Western countries Journal of Gastroenterology and Hepatology, 17 . S268-S273. ISSN 08159319

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Official URL: http://doi.org/10.1046/j.1440-1746.17.s3.12.x

Related URL: http://dx.doi.org/10.1046/j.1440-1746.17.s3.12.x

Abstract

Etiopathogenesis of acute hepatic failure (AHF) in Eastern and Western countries is distinct. In the East hepatitis viruses cause AHF in more than 95% of such cases, while causes of AHF in the West are quite heterogenous. Hepatitis E virus is the major etiological agent of AHF in countries like India where the virus is hyperendemic. Occult HBV infection may also be causing AHF in a sizable proportion of cases in areas where chronic HBV infection frequency is high. Paracetamol causes AHF in about 70% cases in the UK and about 20% cases in USA, whereas in France and Denmark, non-steroidal anti-inflammatory drugs are more frequently associated with AHF. Hepatitis B virus causes AHF in about one-third of cases in the latter two countries.

Item Type:Article
Source:Copyright of this article belongs to Blackwell Publishing Asia Pty Ltd.
ID Code:129153
Deposited On:22 Nov 2022 10:39
Last Modified:22 Nov 2022 10:39

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