Bhunia, Anup ; Patra, Atanu ; Puranik, Vedavati G. ; Biju, Akkattu T. (2013) NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones: Diastereoselective Synthesis of Functionalized Coumarins Organic Letters, 15 (7). pp. 1756-1759. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/ol400562z
Related URL: http://dx.doi.org/10.1021/ol400562z
Abstract
The N-heterocyclic carbene-catalyzed annulation of enals with 2'-hydroxy chalcones afford cyclopentane-fused coumarin derivatives with an excellent level of diastereocontrol. The reaction tolerates a broad range of functional groups; 25 examples are given, and a preliminary mechanistic investigation is provided.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society |
| ID Code: | 128702 |
| Deposited On: | 03 Nov 2022 06:54 |
| Last Modified: | 03 Nov 2022 06:54 |
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