Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles, and Isatins

Bhunia, Anup ; Roy, Tony ; Pachfule, Pradip ; Rajamohanan, Pattuparambil R. ; Biju, Akkattu T. (2013) Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles, and Isatins Angewandte Chemie International Edition, 52 (38). pp. 10040-10043. ISSN 14337851

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Official URL: http://doi.org/10.1002/anie.201304278

Related URL: http://dx.doi.org/10.1002/anie.201304278

Abstract

Mix and match: With isoquinoline as the nucleophilic trigger, multicomponent reactions afforded spirooxazino isoquinoline derivatives, proceeding through 1,4-dipolar intermediates. The use of pyridine as a nucleophile furnished indolin-2-one derivatives, with the reaction likely proceeding through a pyridylidene intermediate.

Item Type:Article
Source:Copyright of this article belongs to WILEY-VCH Verlag GmbH & Co.
Keywords:isatins; multicomponent reactions; oxindoles; synthetic methods
ID Code:128696
Deposited On:03 Nov 2022 06:53
Last Modified:03 Nov 2022 06:53

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